{"id":1398,"date":"2024-07-10T04:29:58","date_gmt":"2024-07-10T04:29:58","guid":{"rendered":"https:\/\/clinic2.hiro-test.net\/hair-transplantation\/?p=1398"},"modified":"2024-11-01T01:28:25","modified_gmt":"2024-11-01T01:28:25","slug":"genetic-research-future","status":"publish","type":"post","link":"https:\/\/clinic2.hiro-test.net\/hair-transplantation\/genetic-research-future\/","title":{"rendered":"\u690d\u6bdb\u3068\u907a\u4f1d\u5b50\u7814\u7a76\uff1a\u672a\u6765\u306e\u907a\u4f1d\u7684\u6cbb\u7642\u6cd5"},"content":{"rendered":"\n

\u73fe\u5728\u306e\u690d\u6bdb\u6cbb\u7642\u6cd5<\/h2>\n\n\n\n

\u73fe\u4ee3\u306e\u690d\u6bdb<\/a>\u6cbb\u7642\u306b\u306f\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e2\u3064\u306e\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

FUE\uff08Follicular Unit Extraction\uff09\uff1a\u6bdb\u5305\u5358\u4f4d\u3092\u500b\u5225\u306b\u63a1\u53d6\u3057\u3001\u79fb\u690d<\/a>\u3059\u308b\u65b9\u6cd5\u3002\u50b7\u8de1\u304c\u5c11\u306a\u304f\u3001\u56de\u5fa9\u304c\u65e9\u3044\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002\u3053\u3061\u3089\u304c\u4e3b\u6d41\u3067\u3059\u3002<\/p>\n\n\n\n

FUT\uff08Follicular Unit Transplantation\uff09\uff1a\u76ae\u819a\u306e\u5e2f\u72b6\u7247\u304b\u3089\u6bdb\u5305\u5358\u4f4d\u3092\u63a1\u53d6\u3057\u3001\u79fb\u690d<\/a>\u3059\u308b\u65b9\u6cd5\u3002\u4e00\u5ea6\u306b\u591a\u304f\u306e\u6bdb\u9aea\u3092\u79fb\u690d<\/a>\u3067\u304d\u308b\u304c\u3001\u50b7\u8de1\u304c\u6b8b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u65b9\u6cd5\u306f\u591a\u304f\u306e\u60a3\u8005\u306b\u52b9\u679c\u7684\u3067\u3059\u304c\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u3055\u3089\u306b\u52b9\u679c\u7684\u3067\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u907a\u4f1d\u5b50\u7814\u7a76\u3068\u8584\u6bdb\u306e\u95a2\u4fc2<\/h2>\n\n\n\n

\u8584\u6bdb<\/a>\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8584\u6bdb<\/a>\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u7814\u7a76\u304c\u9032\u3080\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u539f\u56e0\u3092\u7279\u5b9a\u3057\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u907a\u4f1d\u5b50\u3068\u8584\u6bdb<\/h3>\n\n\n\n

AR\u907a\u4f1d\u5b50\uff1a\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08AR\uff09\u907a\u4f1d\u5b50\u306f\u3001\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA<\/a>\uff09\u306e\u4e3b\u8981\u306a\u539f\u56e0\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u304c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306b\u5909\u63db\u3055\u308c\u308b\u969b\u306e\u611f\u53d7\u6027\u3092\u9ad8\u3081\u3001\u8584\u6bdb<\/a>\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

EDA2R\u907a\u4f1d\u5b50\uff1a\u3053\u306e\u907a\u4f1d\u5b50\u3082AGA\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u3001\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55<\/h3>\n\n\n\n

\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u8584\u6bdb<\/a>\u306e\u6839\u672c\u539f\u56e0\u3092\u89e3\u660e\u3057\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u907a\u4f1d\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u7528\u3044\u305f\u672a\u6765\u306e\u6cbb\u7642\u6cd5\u306b\u3064\u3044\u3066\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u672a\u6765\u306e\u907a\u4f1d\u7684\u6cbb\u7642\u6cd5<\/h2>\n\n\n\n
\"\"<\/figure>\n\n\n\n

1. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\uff08CRISPR\uff09<\/h3>\n\n\n\n

CRISPR\uff08Clustered Regularly Interspaced Short Palindromic Repeats\uff09\u306f\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u4e00\u3064\u3067\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u8584\u6bdb<\/a>\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

AR\u907a\u4f1d\u5b50\u306e\u4fee\u6b63\uff1aAR\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u4fee\u6b63\u3057\u3001DHT\u3078\u306e\u611f\u53d7\u6027\u3092\u4f4e\u6e1b\u3055\u305b\u308b\u3053\u3068\u3067\u3001AGA\u306e\u9032\u884c\u3092\u9632\u3050\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

\u6bdb\u5305\u306e\u518d\u751f\uff1a\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3057\u3001\u6bdb\u9aea\u306e\u518d\u751f\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

2. \u907a\u4f1d\u5b50\u6cbb\u7642<\/h3>\n\n\n\n

\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u4f53\u5185\u306b\u5c0e\u5165\u3057\u3001\u75be\u60a3\u3092\u6cbb\u7642\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002\u8584\u6bdb<\/a>\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u3001\u6bdb\u5305\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u6210\u9577\u56e0\u5b50\u306e\u5c0e\u5165\uff1a\u6bdb\u5305\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u6210\u9577\u56e0\u5b50\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u3001\u6bdb\u9aea\u306e\u518d\u751f\u3092\u4fc3\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\u306e\u4f7f\u7528\uff1a\u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\uff08\u30a6\u30a4\u30eb\u30b9\u306a\u3069\uff09\u3092\u4f7f\u7528\u3057\u3066\u3001\u6cbb\u7642\u7528\u907a\u4f1d\u5b50\u3092\u6bdb\u5305\u306b\u52b9\u7387\u7684\u306b\u5c4a\u3051\u308b\u65b9\u6cd5\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

3. \u5e79\u7d30\u80de\u6cbb\u7642<\/h3>\n\n\n\n
\"\"<\/figure>\n\n\n\n

\u5e79\u7d30\u80de\u306f\u3001\u518d\u751f\u80fd\u529b\u304c\u9ad8\u3044\u7d30\u80de\u3067\u3001\u6bdb\u5305\u306e\u518d\u751f\u306b\u5229\u7528\u3055\u308c\u307e\u3059\u3002\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u6bdb\u5305\u306e\u518d\u751f\u3092\u4fc3\u9032\u3057\u3001\u81ea\u7136\u306a\u9aea\u306e\u6210\u9577\u3092\u4fc3\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u6bdb\u5305\u5e79\u7d30\u80de\uff1a\u6bdb\u5305\u5e79\u7d30\u80de\u3092\u63a1\u53d6\u3057\u3001\u57f9\u990a\u3057\u3066\u304b\u3089\u8584\u6bdb<\/a>\u90e8\u5206\u306b\u79fb\u690d<\/a>\u3059\u308b\u3053\u3068\u3067\u3001\u65b0\u3057\u3044\u6bdb\u9aea\u306e\u6210\u9577\u3092\u4fc3\u3057\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306fGcell\u3092\u7528\u3044\u305f\u6cbb\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u8033\u306e\u5f8c\u308d\u306e\u76ae\u819a\u304b\u3089\u5e79\u7d30\u80de\u3092\u53d6\u308a\u51fa\u3057\u3001\u982d\u90e8\u306b\u6ce8\u5c04\u306b\u3066\u7d30\u80de\u3092\u6ce8\u5165\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

4. \u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9<\/p>\n\n\n\n

\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7814\u7a76\u3059\u308b\u5206\u91ce\u3067\u3059\u3002\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u8584\u6bdb<\/a>\u306e\u9032\u884c\u3092\u6291\u3048\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

DNA\u30e1\u30c1\u30eb\u5316\uff1aDNA\u30e1\u30c1\u30eb\u5316\u306f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u4e00\u3064\u306e\u65b9\u6cd5\u3067\u3059\u3002\u8584\u6bdb<\/a>\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u72b6\u614b\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u6bdb\u9aea\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\uff1a\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3082\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u3064\u3067\u3059\u3002\u7279\u5b9a\u306e\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u3092\u5236\u5fa1\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u5b9f\u7528\u5316\u306b\u5411\u3051\u305f\u8ab2\u984c\u3068\u5c55\u671b<\/h2>\n\n\n\n

1. \u5b89\u5168\u6027\u306e\u78ba\u4fdd<\/h3>\n\n\n\n

\u907a\u4f1d\u5b50\u6cbb\u7642\u3084\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u9ad8\u5ea6\u306a\u6280\u8853\u3092\u8981\u3057\u3001\u5b89\u5168\u6027\u306e\u78ba\u4fdd\u304c\u6700\u91cd\u8981\u8ab2\u984c\u3067\u3059\u3002\u6cbb\u7642\u306e\u5b9f\u7528\u5316\u306b\u5411\u3051\u3066\u306f\u3001\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n

2. \u52b9\u679c\u306e\u6301\u7d9a\u6027<\/h3>\n\n\n\n

\u6cbb\u7642\u306e\u52b9\u679c\u304c\u9577\u671f\u9593\u6301\u7d9a\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u907a\u4f1d\u5b50\u6cbb\u7642\u3084\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u52b9\u679c\u304c\u6301\u7d9a\u7684\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u3001\u9577\u671f\u7684\u306a\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n

3. \u30b3\u30b9\u30c8\u3068\u30a2\u30af\u30bb\u30b9<\/h3>\n\n\n\n

\u9ad8\u984d\u306a\u6cbb\u7642\u8cbb\u306f\u3001\u591a\u304f\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u5927\u304d\u306a\u969c\u58c1\u3068\u306a\u308a\u307e\u3059\u3002\u6cbb\u7642\u6cd5\u304c\u5e83\u304f\u666e\u53ca\u3057\u3001\u30b3\u30b9\u30c8\u304c\u4f4e\u6e1b\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u591a\u304f\u306e\u4eba\u3005\u304c\u5229\u7528\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\u307e\u3068\u3081<\/h2>\n\n\n\n

\u690d\u6bdb<\/a>\u3068\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u8584\u6bdb<\/a>\u6cbb\u7642\u306e\u672a\u6765\u306f\u660e\u308b\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u3001\u5e79\u7d30\u80de\u6cbb\u7642\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306a\u3069\u306e\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u3001\u3088\u308a\u52b9\u679c\u7684\u3067\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u4f9b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u8584\u6bdb<\/a>\u306b\u60a9\u3080\u65b9\u306f\u3001\u3053\u308c\u3089\u306e\u6700\u65b0\u6280\u8853\u306e\u9032\u5c55\u306b\u6ce8\u76ee\u3057\u3001\u5c06\u6765\u7684\u306a\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3068\u3057\u3066\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u907a\u4f1d\u5b50\u7814\u7a76\u306b\u3088\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u5b9f\u7528\u5316\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u5065\u5eb7\u306a\u9aea\u3092\u53d6\u308a\u623b\u3057\u3001\u81ea\u4fe1\u3092\u6301\u3063\u3066\u751f\u6d3b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3067\u3057\u3087\u3046\u3002\u305c\u3072\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u306b\u6765\u9662\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u73fe\u5728\u306e\u690d\u6bdb\u6cbb\u7642\u6cd5 \u73fe\u4ee3\u306e\u690d\u6bdb\u6cbb\u7642\u306b\u306f\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e2\u3064\u306e\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002 FUE\uff08Follicular Unit Extraction\uff09\uff1a\u6bdb\u5305\u5358\u4f4d\u3092\u500b\u5225\u306b\u63a1\u53d6\u3057\u3001\u79fb\u690d\u3059\u308b\u65b9\u6cd5\u3002\u50b7\u8de1\u304c\u5c11\u306a\u304f\u3001\u56de\u5fa9\u304c\u65e9\u3044\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002\u3053\u3061\u3089\u304c\u4e3b\u6d41\u3067\u3059\u3002 FUT\uff08Follicular Unit Transplantation\uff09\uff1a\u76ae\u819a\u306e\u5e2f\u72b6\u7247\u304b\u3089\u6bdb\u5305\u5358\u4f4d\u3092\u63a1\u53d6\u3057\u3001\u79fb\u690d\u3059\u308b\u65b9\u6cd5\u3002\u4e00\u5ea6\u306b\u591a\u304f\u306e\u6bdb\u9aea\u3092\u79fb\u690d\u3067\u304d\u308b\u304c\u3001\u50b7\u8de1\u304c\u6b8b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u3053\u308c\u3089\u306e\u65b9\u6cd5\u306f\u591a\u304f\u306e\u60a3\u8005\u306b\u52b9\u679c\u7684\u3067\u3059\u304c\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u3055\u3089\u306b\u52b9\u679c\u7684\u3067\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u907a\u4f1d\u5b50\u7814\u7a76\u3068\u8584\u6bdb\u306e\u95a2\u4fc2 \u8584\u6bdb\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8584\u6bdb\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u7814\u7a76\u304c\u9032\u3080\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u539f\u56e0\u3092\u7279\u5b9a\u3057\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002 \u907a\u4f1d\u5b50\u3068\u8584\u6bdb AR\u907a\u4f1d\u5b50\uff1a\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08AR\uff09\u907a\u4f1d\u5b50\u306f\u3001\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306e\u4e3b\u8981\u306a\u539f\u56e0\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u304c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306b\u5909\u63db\u3055\u308c\u308b\u969b\u306e\u611f\u53d7\u6027\u3092\u9ad8\u3081\u3001\u8584\u6bdb\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002 EDA2R\u907a\u4f1d\u5b50\uff1a\u3053\u306e\u907a\u4f1d\u5b50\u3082AGA\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u3001\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55 \u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u8584\u6bdb\u306e\u6839\u672c\u539f\u56e0\u3092\u89e3\u660e\u3057\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u907a\u4f1d\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u7528\u3044\u305f\u672a\u6765\u306e\u6cbb\u7642\u6cd5\u306b\u3064\u3044\u3066\u8aac\u660e\u3057\u307e\u3059\u3002 \u672a\u6765\u306e\u907a\u4f1d\u7684\u6cbb\u7642\u6cd5 1. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\uff08CRISPR\uff09 CRISPR\uff08Clustered Regularly Interspaced Short Palindromic Repeats\uff09\u306f\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u4e00\u3064\u3067\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u8584\u6bdb\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002 AR\u907a\u4f1d\u5b50\u306e\u4fee\u6b63\uff1aAR\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u4fee\u6b63\u3057\u3001DHT\u3078\u306e\u611f\u53d7\u6027\u3092\u4f4e\u6e1b\u3055\u305b\u308b\u3053\u3068\u3067\u3001AGA\u306e\u9032\u884c\u3092\u9632\u3050\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u6bdb\u5305\u306e\u518d\u751f\uff1a\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u3092\u4fee\u6b63\u3057\u3001\u6bdb\u9aea\u306e\u518d\u751f\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002 2. \u907a\u4f1d\u5b50\u6cbb\u7642 \u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u4f53\u5185\u306b\u5c0e\u5165\u3057\u3001\u75be\u60a3\u3092\u6cbb\u7642\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002\u8584\u6bdb\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u3001\u6bdb\u5305\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002 \u6210\u9577\u56e0\u5b50\u306e\u5c0e\u5165\uff1a\u6bdb\u5305\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u6210\u9577\u56e0\u5b50\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u3001\u6bdb\u9aea\u306e\u518d\u751f\u3092\u4fc3\u3057\u307e\u3059\u3002 \u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\u306e\u4f7f\u7528\uff1a\u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\uff08\u30a6\u30a4\u30eb\u30b9\u306a\u3069\uff09\u3092\u4f7f\u7528\u3057\u3066\u3001\u6cbb\u7642\u7528\u907a\u4f1d\u5b50\u3092\u6bdb\u5305\u306b\u52b9\u7387\u7684\u306b\u5c4a\u3051\u308b\u65b9\u6cd5\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002 3. \u5e79\u7d30\u80de\u6cbb\u7642 \u5e79\u7d30\u80de\u306f\u3001\u518d\u751f\u80fd\u529b\u304c\u9ad8\u3044\u7d30\u80de\u3067\u3001\u6bdb\u5305\u306e\u518d\u751f\u306b\u5229\u7528\u3055\u308c\u307e\u3059\u3002\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u6bdb\u5305\u306e\u518d\u751f\u3092\u4fc3\u9032\u3057\u3001\u81ea\u7136\u306a\u9aea\u306e\u6210\u9577\u3092\u4fc3\u3057\u307e\u3059\u3002 \u6bdb\u5305\u5e79\u7d30\u80de\uff1a\u6bdb\u5305\u5e79\u7d30\u80de\u3092\u63a1\u53d6\u3057\u3001\u57f9\u990a\u3057\u3066\u304b\u3089\u8584\u6bdb\u90e8\u5206\u306b\u79fb\u690d\u3059\u308b\u3053\u3068\u3067\u3001\u65b0\u3057\u3044\u6bdb\u9aea\u306e\u6210\u9577\u3092\u4fc3\u3057\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306fGcell\u3092\u7528\u3044\u305f\u6cbb\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u8033\u306e\u5f8c\u308d\u306e\u76ae\u819a\u304b\u3089\u5e79\u7d30\u80de\u3092\u53d6\u308a\u51fa\u3057\u3001\u982d\u90e8\u306b\u6ce8\u5c04\u306b\u3066\u7d30\u80de\u3092\u6ce8\u5165\u3057\u307e\u3059\u3002 4. \u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9 \u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7814\u7a76\u3059\u308b\u5206\u91ce\u3067\u3059\u3002\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u8584\u6bdb\u306e\u9032\u884c\u3092\u6291\u3048\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 DNA\u30e1\u30c1\u30eb\u5316\uff1aDNA\u30e1\u30c1\u30eb\u5316\u306f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u4e00\u3064\u306e\u65b9\u6cd5\u3067\u3059\u3002\u8584\u6bdb\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u72b6\u614b\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u6bdb\u9aea\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002 \u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\uff1a\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3082\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u3064\u3067\u3059\u3002\u7279\u5b9a\u306e\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u3001\u6bdb\u5305\u306e\u6210\u9577\u30b5\u30a4\u30af\u30eb\u3092\u5236\u5fa1\u3057\u307e\u3059\u3002 \u5b9f\u7528\u5316\u306b\u5411\u3051\u305f\u8ab2\u984c\u3068\u5c55\u671b 1. \u5b89\u5168\u6027\u306e\u78ba\u4fdd \u907a\u4f1d\u5b50\u6cbb\u7642\u3084\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u9ad8\u5ea6\u306a\u6280\u8853\u3092\u8981\u3057\u3001\u5b89\u5168\u6027\u306e\u78ba\u4fdd\u304c\u6700\u91cd\u8981\u8ab2\u984c\u3067\u3059\u3002\u6cbb\u7642\u306e\u5b9f\u7528\u5316\u306b\u5411\u3051\u3066\u306f\u3001\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u5fc5\u8981\u3067\u3059\u3002 2. \u52b9\u679c\u306e\u6301\u7d9a\u6027 \u6cbb\u7642\u306e\u52b9\u679c\u304c\u9577\u671f\u9593\u6301\u7d9a\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u907a\u4f1d\u5b50\u6cbb\u7642\u3084\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u52b9\u679c\u304c\u6301\u7d9a\u7684\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u3001\u9577\u671f\u7684\u306a\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002 3. \u30b3\u30b9\u30c8\u3068\u30a2\u30af\u30bb\u30b9 \u9ad8\u984d\u306a\u6cbb\u7642\u8cbb\u306f\u3001\u591a\u304f\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u5927\u304d\u306a\u969c\u58c1\u3068\u306a\u308a\u307e\u3059\u3002\u6cbb\u7642\u6cd5\u304c\u5e83\u304f\u666e\u53ca\u3057\u3001\u30b3\u30b9\u30c8\u304c\u4f4e\u6e1b\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u591a\u304f\u306e\u4eba\u3005\u304c\u5229\u7528\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002 \u307e\u3068\u3081 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